Abstract: [Objective]The experiment was designed to analyze influence of early weaning on biochemistry indicators in serum of Chinese Merino lamb.[Method]There are three groups in the experiment! former groups(Gl &G2) are experiment group with early weaning at 40 days and 60 days respectively, fed with milk replacer.While control group(G3) was fed with milk from their ewes.The indicators in serum measured include:TPi ALB,GLOB, A/G,SUN,CHOL,GLU,TG,AST, ALT,ALP.LDH, LDL,HDL,Na, K,Cl,Ca,P,Mg.[Result]The results showed that as for SUN,Gl&G2 are 4.87 mmol/L and 3.9 mmol/L higher than that of G3,significantly(P < 0.05); as for HDL , the two groups are 0.14 mmol/L and 0.1 mmol/L lower than that of G3, significantly (P < 0.05); for AST, the two groups are 17.25 U/L and 11.8 U/L lower than that of G3,significantly (P < 0.05);as for CHOL and GLU,GI is 0.33 mmol/L, and 0.51 mmol/L lower than that of G3,significantly (P<0.05);as for ALT, Na and C1,G1 is 4.22 U/L, 4.63 mmol/L and 3.14 mmol/L lower than that of G3,significantly (P < 0.05) ;as for Mg GI is 0.05 mmol/L higher than that of G3,significantly (P<0.05); as for LDH GLT is 90.14 U/L higher than that of G3,significantly(P<0.05).[Conclusion] As a result, change of SUN and HDL in serum may reflect: early weaning has effect on balance among AA and protein metabolism to some extent.Meantime, LDH, AST,and GOP are lower in serum due to early weaning ,it can enhance their ability of anti - stress.In addition, activity of ALP reflect growth speed and production performances, no significant difference of ALP between experiment groups and control group, so early weaning has not impact on growth and development of Chinese Merino lamb in this experiment.

摘要： [目的]对早期断奶中国美利奴羊(新疆型)羔羊血清生化指标的测定与分析,研究主要血清生化指标对其早期断奶的影响.[方法]试验分为三组,试验Ⅰ组(40日龄断奶组)、试验Ⅱ组(60日龄断奶组)、试验Ⅲ(对照组),试验组用代乳料在40和60 d早期断奶,对照组随母羊哺乳.测定指标包括: TP、 ALB、GLOB、A/G、SUN、CHOL、GLU、TG、AST、ALT、ALP、LDH、LDL、HDL、Na、K、Cl、TCa、P、Mg.[结果]试验组SUN分别高于对照组4.87和3.9 mmol/L,差异显著(P＜0.05);试验组HDL分别低于对照组0.14 和0.1 mmol/L,差异显著(P＜0.05);试验组AST分别低于对照组17.25和11.8 U/L,差异显著(P＜0.05);试验Ⅰ组CHOL、GLU分别低于对照组0.33和0.51 mmol/L,差异显著(P＜0.05);试验Ⅰ组ALT低于对照组4.22 U/L,差异显著(P＜0.05);试验Ⅰ组Na,Cl分别低于对照组4.63和3.14 mmol/L,差异显著(P＜0.05);试验Ⅰ组Mg高于对照组0.05 mmol/L,差异显著(P＜0.05).试验Ⅱ组LDH低于对照组90.14 U/L,差异显著(P＜0.05);其他相关指标试验组与对照组差异不显著(P＞0.05).[结论]早期断奶提高了中国美利奴羊(新疆型)羔羊SUN含量,显著降低了HDL含量,在一定程度上影响了动物体内蛋白质代谢和氨基酸之间的平衡状况及体内胆固醇的代谢.同时早期断奶降低血清LDH、AST、GOP含量,对于提高机体抗应激能力及缓解肝脏、心脏和肾脏等内脏器官的损伤程度具有重要作用.另外血清碱性磷酸酶(ALP)活性高低反应了生长速度和生产性能.试验中试验组与对照组ALP含量差异不显著,表明早期断奶对于羔羊的生长和发育没有影响.