Abstract: 【 Objective 】 Colorado potato beetle, Leptinotarsa decemlineata (Say) (Coleoptera: Chrysomelidae), is a destructive invasive pest that has been listed as a serious foreign quarantine insect pest in China, causing devastating damage to potato and other solanaceae crops. It is effective and environmental-friendly to utilize parasitoids to control Colorado potato beetle damage. This study aims to investigate parasitic wasp's resource in Xinjiang to obtain and use local parasitoids as natural enemies to fight against that invasive pest. This research has positive implications for biological control of Colorado potato beetle. 【 Method 】We conducted a large scale field investigation and collected large number of insects in the potato planting area of Ili, Xinjiang between July and August of 2013 and 2014. We also collected eggs and larvae of Colorado potato beetle in fields to obtain parasitic natural enemies after the artificial breeding in laboratory.【 Result 】We obtained two parasitic wasps, Oomyzus sp. (Hymenoptera: Eulophidae) and Telenomus sp. (Hymenoptera: Scelionidae), as egg parasitoids of Colorado potato beetle. We observed and reported the morphological and biological characters of these parasitoids for the first time, and discussed their potential for the control of Colorado potato beetle. 【 Conclusion 】Oomyzus sp. and Telenomus sp. are egg parasitoids of Colorado potato beetle, and probably potential parasitic natural enemies for biological control of Colorado potato beetle after further research on their parasitic biological characteristics.