Abstract: 【Objective】 Based on the medicinal value of Lycium barbarum, the contents and primary speciation of ten kinds of macro and trace elements in Jinghe wolfberry, Xinjiang, were analyzed by inductively coupled plasma mass spectrometry (ICP-MS). 【Method】Water soluble、suspended, organic and inorganic states in extract solution were separated by 0.45 μm filter membrane and D101 macroporous adsorption resin. Water decoction residues were extracted by acetone and hydrochloric acid successively and the contents of the ten elements in different states were determined by ICP-MS.【Result】The relative standard deviation of ten elements of Mg , Zn , Ca , Fe , Cu , Mn , As , Se , Cd and Pb of the ten kinds of elements in the Jinghe Fructus Lycii was between 20.5% and 47.8% , and the relative standard deviation of them was 0.12%-1.25% ; The recovery rate was 84.60%-106.1%.【Conclusion】The study of this work has certain significance for the establishment of detection method and the determination of the form and medicinal value of macro and trace elements in Jinghe wolfberry (Lycium barbarum L.).