Abstract: 【Objective】 In view of the problem of the quality decline caused by the incomplete coloring and unreasonable use of regulators in Table grape in Xinjiang, the research object of this study was to compare the advantages and disadvantages of the independent R & D regulator with the marketed regulator and foliar fertilizer, and to study the influence of the independent R & D foliar regulator on the coloring and quality of grape. 【Methods】 In this study, the effects of spraying different regulators and foliar fertilizer on the coloration and quality of grape were studied by using grape ('Red Earth') as material and single -factor random block test design. 【Results】 Compared with other treatments, spraying the self-developed foliar conditioner could effectively increase the color parameters of grapes, enhance the accumulation of anthocyanins, gradually increase the activity of coloring-related enzymes, increase the vertical and horizontal diameter of fruits, and increase the swelling rate at a high level. With the increase of the content, the hardness of the peel decreased with time. 【Conclusion】 Compared with the market regulator and foliar fertilizer, all the indexes were in high level, which could effectively improve the coloration and quality of grape fruit. Compared with marketing regulator and foliar fertilizer, all the indexes of leaf regulator developed independently are in high level, which can effectively improve the color and quality index of grape fruit.