Abstract: 【Objective】 To explore the impact of drought on millet germination, screen out drought resistance related indicators during millet germination, and further clarify the response mechanism of antioxidant enzymes in different millet varieties to drought stress during germination.the research results can provide a reference for selecting and cultivating millet varieties suitable for planting in Xinjiang. 【Methods】 Using 20% polyethylene glycol (PEG-6000) to simulate drought stress during germination, the drought resistance of 15 millet varieties was evaluated, and the changes in the activities of SOD, POD, CAT, and GR of 15 varieties under drought stress were measured to study their internal situation. 【Results】 (1) Under drought stress, the germination potential, germination rate, radicle length, plumule length, fresh weight, and dry weight of the tested millet varieties were inhibited to varying degrees, with a relatively small impact on the germination rate, but the root buds of several varieties such as Mengfenggu 7 had a promoting effect.(2) A comprehensive evaluation of drought resistance was conducted using the membership function method. The drought resistance of 15 millet varieties was graded, including 5 strong drought resistant varieties, 4 moderate drought resistant varieties, 5 drought sensitive varieties, and 1 drought extremely sensitive type. (3) Under drought stress, the activities of antioxidant enzymes SOD, POD, CAT, and GR in millet seedlings of different varieties increased, and the drought tolerant varieties themselves had relatively high antioxidant enzyme activities and could maintain high levels under drought stress. 【Conclusion】 Overall, Mengfenggu 7 has the best drought resistancehe.