Abstract: 【Objective】 To investigate thoroughly the effects of mixed salt alkali stress on peanut seed germination and seedling growth in the hope of improving the planting structure of saline alkali land in Xinjiang and increasing the peanut planting area. 【Methods】 This study used Huayu 25 as the experimental material and artificially simulated mixed salt alkali stress conditions to determine the germination rate, germination potential, germination index, vitality index, salt damage rate, and root and stem length of peanut seedlings, in order to provide a basis for the effective utilization of saline alkali land and the cultivation of salt tolerant varieties. 【Results】 (1) Under high concentration stress, the mixed saline alkali solution composed of Cl^- and SO₄^2- has a more severe inhibitory effect on peanut seed germination; When the pH of the mixed saline alkali solution was greater than 10, the inhibitory effect on the growth of peanut seed primary seedlings was severer; (2) Different concentrations of mixed salt alkali stress had varying degrees of impact on germination rate, germination potential, germination index, vitality index, salt damage rate, root length, and stem length. High concentrations of mixed salt alkali would have an inhibitory effect on peanut seed germination; (3) The salt and alkaline tolerance of peanuts to each treatment was B>C>D>E>A in descending order. 【Conclusion】 Different mixed salt alkali components and concentrations have different effects on peanut seeds, and the seed germination period is the most sensitive period for plants to salt alkali stress.