Abstract: 【Objective】 This project aims at studying the changes in ecosystem service value (ESV) caused by land use changes under multiple scenarios, as well as the spatiotemporal changes and trade-off synergies of ecosystem service functions in the hope of providing decision-making reference. 【Methods】 Taking Turpan City, an extremely arid region, as an example, based on the Patch-generating Land Use Simulation Model (PLUS), equivalent factor method, spatial autocorrelation, ESCI, ESTD models, and other methods, the ESV changes, spatiotemporal distribution characteristics, and trade-off synergy relationships in Turpan City from 2010 to 2035 (natural development, farmland protection, ecological protection) were estimated and predicted. 【Results】 (1) From 2010 to 2020, the grassland and construction land areas in Turpan City increased by 0.16×10⁴hm² and 1.98×10⁴hm², respectively, while the cultivated land, forest land, water area, and unused land decreased by 0.51×10⁴, 0.46×10⁴, 0.33×10⁴, and 0.85×10⁴hm², respectively. Under these three scenarios, the reduction rate of water area slowed down and the expansion degree of construction land decreased. (2) In 2010, 2015 and 2020, the ESV in the study area was 213.75×10⁸ Yuan, 209.23×10⁸ Yuan and 205.78×10⁸ Yuan, respectively, showing a linear downward trend, with a total decrease of 7.97×10⁸ Yuan;Under the three simulated scenarios of natural development scenario, cultivated land protection and ecological protection, the ESV showed an upward trend, and the spatial distribution characteristics were "high in the northern mountainous area and low in the southern desert" (3) In 2035, under the three scenarios, the main focus will be on synergy among various ecosystem service functions. The distribution of "high-high" and "low-low" collaborative agglomeration areas is likely to be highly consistent with the distribution of ESV high and low value areas, and the balance relationship would be scattered in the border area between urban and agricultural spaces and other local areas. 【Conclusion】 The ESV of natural development, cultivated land protection and ecological protection scenario was 207.90×10⁸ Yuan、213.06×10⁸ Yuan and 240.40×10⁸ Yuan, all higher than that in 2020 ESV.